脑心通胶囊在缺血性脑卒中二级预防中的应用

A Analysis of Applying Naoxintong Capsule to Secondary Prevention of Ischemic Cerebral Stroke

目的比较脑心通胶囊和阿司匹林肠溶片在缺血性脑卒中二级预防中的疗效和安全性。方法将90例缺血性脑卒中患者随机分为两组:脑心通胶囊组和阿司匹林组各45例。脑心通胶囊组给予步长脑心通胶囊口服,0.4g/粒,2粒/次,3次/d。阿司匹林组给予阿司匹林肠溶片口服,25mg/片,3片/次,1次/d。合并高血压、糖尿病和高血脂者,分别给予降压、降糖和降脂治疗,吸烟者戒烟。随访1年,比较两组患者缺血性脑卒中复发率和药物不良反应发生率。结果两组患者缺血性脑卒中复发率、不良反应发生率间差异均有统计学意义(P<0.05)。结论脑心通胶囊在缺血性脑卒中二级预防中的疗效优于阿司匹林,安全性较高,值得推广应用。

Objective To object therapeutic effect and Security of applying Naoxintong Capsule and aspirin to secondary prevention of ischemic cerebral stroke. Methods 90 patients with isehemic cerebral stroke were randomly divided into the Naoxintong Capsule group （ n = 45 ） and the aspirin group （ n = 45 ）. Patients in Naoxintong Capsule group received Naoxintong Capsule once 2 grain, three times a day. Pationts in aspirin group received aspirin enteric - coated tablets once 75mg, one time a day. Two group patients were followed up one year, and recurrences rate of ischemic cerebral stroke and The adverse drug reaction rates in two group patients were compared. Results Recurrences rate of ischemic cerebral stroke and The adverse drug reaction rates are low in Naoxintong Capsule group than aspirin group. Conclusion Therapeutic effect and Security of Naoxintong Capsule in secondary prevention of isehemic cerebral stroke is better than aspirin, which is worth spreading and applying.