摘要
目的:探讨抑郁症对急性ST段抬高型心肌梗死(STEMI)经皮冠状动脉介入治疗(PCI)后心率变异性(HRV)影响。方法:随机选择62例合并抑郁症STEMI患者(包括持续抑郁患者26例和一过抑郁症患者36例)和102名非合并抑郁症患者。分别于术后1周和3个月通过BECK抑郁自评问卷(BDI)进行心理测评,并且利用24h动态心电图检测心率变异性。结果:HRV在STEMI患者PCI术后随时间恢复,但在合并抑郁症患者中仍低于非合并抑郁症患者。结论:HRV在合并抑郁症状患者中明显降低,反映其自主神经功能低下,并且与心梗后升高的心源性死亡相关。
Objective: To evaluate the significance of depression on the HRV in patients with STEMI treated with PCI. Method : The study group consisted of 164 patients with STEMI treated with PCI that was divided into two groups: Group A :102 persistently no depressed patients,and Group B :62 patients with depression, including 26 persistently depressed patients and 36 remittent depressed patients. All underwent 24 -hour ambulatory electrocardiographic monitoring at 1 week and 3 months after PCI. Result: HRV were significantly lower in patients with depression than those without depression and higher following with the time after PCI. Conclusion: Depression is associated with reduced HRV in patients with STEMI. Autonomic cardiac regulatory system dysfunction, which is reflected by decreased HRV, is a plausible mechanism linking depression to increase cardiac mortality in post - MI patients.
出处
《河北医学》
CAS
2009年第9期1009-1012,共4页
Hebei Medicine