肺炎患儿急性期和恢复期血浆维生素A水平分析

An Analysis of Serum Vitamin A in the Acute and Recovery Stages of Pneumonia in Children

目的:研究肺炎患儿急性期、恢复期血浆维生素A(VA)的变化规律。方法:(1)比较173名2岁以下急性期肺炎患儿和182名正常同龄儿血浆VA水平;(2)随访患儿家长同意并在恢复期抽血的30名VA缺乏肺炎患儿恢复期VA水平,比较患儿急性期、恢复期VA水平。结果:(1)肺炎患儿血浆VA低于正常健康小儿[(0.99±0.60)vs(1.17±0.33)μmol/L],差异有统计学意义(P<0.05);(2)恢复期患儿血浆VA水平较急性期明显升高[(0.77±0.33)vs(0.48±0.12)μmol/L],差异有统计学意义(P<0.01),但仍低于正常健康小儿水平。结论:肺炎患儿血浆VA水平较同龄正常健康小儿明显下降,维生素A缺乏肺炎患儿恢复期血浆VA水平较急性期升高,差异有统计学意义,但仍低于正常水平。

Objective：The aim of this study was to examine the concentration of plasma vitamin A in the acute and recovery phases of pneumonia. Methods： （1） To compare the concentration of vitamin A between 173 patients under 2-year-old who were in the acute stage of pneumonia and 182 healthy children at the same age. （2） During follow-up visits blood of 30 VAD children were drawn in their recovery phases and compare with those in acute stage in the level of VA. Results： （ 1 ） The plasma VA concentration of the pneumonia children was obviously lower than that in healthy children [ （0.99 ± 0.60） vs （ 1.17 ± 0.33 ） μmoL/L, P 〈 0.05 ]. （2） In the recovery stage, the level of VA concentration was obviously higher than that in the acute stage [ （0.77 ±0.33） vs （0.48 ±0.12） μmoL/L, P 〈0.01 ] but still lower than the healthy children. Conclusions： （ 1 ） The plasma VA concentration of children with pneumonia is lower than that of healthy children. （2） The level of VA of the children with pneumonia in the recovery stage is higher than that in the acute stage, but still lower than the normal.