子宫切除对卵巢功能影响的临床研究

Study the effect of hysterectomy on ovarian

目的:探讨子宫切除不同术式对卵巢功能的影响。方法:对39例月经周期规则、卵巢正常、手术方式不同的子宫肌瘤患者,采用放射免疫法测定术前及术后性激素(FSH、E2)水平,以及术后是否出现卵巢功能衰退。结果:术后2周子宫全切组及次全切组患者E2下降,与术前相比差异无统计学意义(P>0.05),FSH升高,与术前相比差异有统计学意义(P<0.05);术后3～12个月E2、FSH与术前相比差异无统计学意义(P>0.05);手术前后全切组与次全切组相比,E2、FSH变化差异均无统计学意义。结论:子宫切除会引起卵巢功能暂时性下降,可于术后逐渐恢复,与手术方式无明显关系。

Objective： To study the effect of hysterectomy on ovarian. Methods：Thirty-nine women with hysteromyoma were studied, undergoing hysterectomy in different ways, including total hysterectomy, subtotal hysterectomy and hysteromyomectomy,and having regular period and normal overy. Their hormone （FSH,E2）level in blood was determined with the method of radioimmunoassy before and after operation. And they were asked about symptoms of bypoovafia. Results：2 weeks ＇after operation,those undergoing total and subtotal hysterectomy found their E2 decreased, compared with that of preoperation with no significant difference （P〉0.05）, and FSH increased,compared with that of preoperation with no significant differences（P〈0.05） for 3 to 12 monthes after operation,but found no significant change in E2 and FSH level（P〉0.05）, before and after operation, comparing with that of the total and subtotal hysterectomy who showed no significant difference. Conclusion： Hysterectomy can make ovarian function decrease temporarily ,and return to normal gradually,and this does not correlate with operative technique.