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钙通道阻滞剂对血管平滑肌的作用机制与临床应用 被引量:2

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摘要 目的:评价钙通道阻滞剂(calcium channel blockers,CCB)的临床疗效及安全性,以供临床医师合理用药参考。方法:根据国内、外近期有关CCB的试验结果和文献进行评价、分析。结果:CCB已成为治疗心血管疾病的基本药物之一,特别是在抗高血压方面尤为突出。结论:钙通道阻滞剂对血管平滑肌、支气管平滑肌、泌尿道平滑肌、子宫平滑肌、胆道平滑肌有明显的作用,在临床上有着广泛的应用前景。
出处 《中国当代医药》 2009年第7期166-166,共1页 China Modern Medicine
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  • 1Simon A, Gariepy J, Moyse D, et al. Differential effects of nifedipine and CO- anfilozide on the progression of early carotid wall changes[ J ]. Circulation,2001, 103 (24) : 2949-2954.
  • 2Lubsen J,Wagener G,Kirwan BA,et al. Effect of long-acting nifedilpine on mortality and cardiovascular mortality in patients with symptomatic stable angina and hypertension: the ACTION trial [ J ]. J Hypertens ,2005,23:641-648.
  • 3Nissen SE,Tuzcuy EM,Libby P,et al. Effect of antihypertension agents on cardiovascular events in patients with coronary disease and normal blood pressure:the CAMELOT study : a randomized controlled trial [ J ]. JAMA, 2004,292 ( 18 ) : 2217-2226.
  • 4Zanchetti A, Bond MG, Hennig M,et al. European Lacidipine Study on Atherosclerosis investigators Calcium antagonist lacidipine slows down progression of asymptomatic carotid atherosclerosis : principal results of the European Lacidipine Study on Atherosclerosis ( ELSA ), a randomized, double-blind, long-term trial [ J ]. Circulation,2002,106 (19) :2422-2427.
  • 5Pitt B .Bymgton RF,Furberg CD,et al. Effect of amlodipinc on the progression of atherosclerosis and the occurrence of clinical events. PREVENT Investigators [ J ]. Circulation,2000,102 : 1503-1510.
  • 6Stepien O, Gogusev J,Zhu DL, et al. Amlodipine inhibition of serum thrombin, or fibroblast growth factor induced vascular smooth muscle cell proliferation[ J ]. J Cardiovasc Pharmacol, 1998,31 ( 5 ) :786-793.
  • 7Cristofofi P, Lanzoni A, Quartaroli M, et al. The calcium-channel blocker lacidipine reduces the development of atherosclerotic lesions in the apoE-deficient mouse [J]. J Hypertens,2000,18(10) : 1429-1436.
  • 8Turgan N ,Habif S ,Kabaroglu CG,et al. Effects of the calcium channel blocker amlodipine on serum and aortic cholesterol,lipid peroxidation, antioxidant status and aortic histology in cholesterol-fed rabbits[ J ]. J Biomed Sci, 2003,10 ( 1 ) : 65 -72.
  • 9Franzoni F,Santoro G,Regoli F,et al. An in vitro study of the peroxyl and hydroxyl radical scavenging capacity of the calcium antagonist flaillodipine[ J ]. Biomed Pharmacother,2004,58:423-426.
  • 10Matsubara M, Hasegawa K. Benidipine a dihydropyridine-calcium channel blocker prevents lysophosphatidylcholine-induced initry and reactive oxygen species production in human aortic endothelial cells[ J ]. Atherosclerosis ,2005,178:57- 66.

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同被引文献34

  • 1葛鹏,董强.钙通道阻滞剂对急性胰腺炎的作用及其机制研究[J].中国新医药,2003,2(5):36-37. 被引量:4
  • 2费娜,许丽珍.钙离子拮抗剂对帕金森病的神经保护作用[J].中国误诊学杂志,2006,6(7):1244-1246. 被引量:5
  • 3王祥民.钙通道阻滞剂在肝硬化治疗中的应用[J].华北煤炭医学院学报,2006,8(2):163-164. 被引量:2
  • 4董其勇,向萍.钙拮抗剂的药理作用及临床应用[J].现代医药卫生,2007,23(12):1808-1810. 被引量:2
  • 5Yamamoro T,Niwa Y,Kauakami H.The effect of nilvadipine,a calcium-channel blockers,on hemidynalnics[J].Glaucoma,1998,7(5):301-305.
  • 6Strem K,Mafulla B,Wolztm M.Reversal of endothelin-1-induced ocular hemodymamic effects by low-dose nifedipine in human[J].Clin Pharmacol Ther,1998,63(1):54-63.
  • 7邓一芸 陈晓明 宋广瑶.原发性开角型青光眼患者在寒冷刺激及服用钙离子通道阻滞剂后视盘血流的变化.中华眼底病杂志,2000,16(2):412-413.
  • 8张楠 美丽班 黄红雨.钙通道阻滞剂临床应用进展.新医学学刊,2008,5(9):1521-1522.
  • 9Mclaughlin VV,Archer SL,Badesch DB,et al. ACCF/AHA 2009 ex- pert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American College of Chest Physicians, American Thoracic Society,Inc,and the Pulmonary Hypertension As- sociation[J]. Circulation,2009,119(16): 2250-2294.
  • 10Strange JW,Wharton J,Phillips PG,et al. Recent insights into the pathogenesis and therapeuty of pulmonary hypertension[J]. Clin Sei(Lond), 2002, 102:253-260.

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