一起空调系统导致上呼吸道感染样军团病爆发的调查

Investigation of An Legionnaires' Disease Outbreak Associated with Contaminated Air - Conditioning System

１９９７年６月北京某写官楼员工发生一起上呼吸道感染样（上感样）疫情。为查明爆发原因，采用流行病学病例－对照调查研究方法，分别对病例组、对照组进行嗜肺军团菌（Ｌｐ）抗体－１￣１４型血清学检测，并对大厦空调系统采们进行细菌学培养检测。结果：该次爆发疫情的扁桃体炎罹患率为６１．８６％，上感罹患率３４．６２％，统计学检验发热与扁体关系密切（Ｘ＾２＝７７．８８，Ｐ〈０．０１）；上感病例ＬＰ９、１０、１２。

An outbreak of upper respiratory infection (influenza-like syndrom) took place among the staff members of a large office building in Beiiing, June, 1997. To understand the cause of the outbreak, with a case-control study with serological antibodies detection against serogroup 1 to 14 of Legionnaires' disease bacteria (LDB) and bacteriological test and culture on samples collected from the air-conditioning system of the office building was performed. The findings showed that the attack rates of tongillitis and upper respiratory infection were 61.86% and 34.62% respectively. The relation was statistically significant between the symptoms of fever and tonsillitis in the cases (χ~2 =77.88, P<0.01). The positive rates of LDB antibodies on serogroups 9, 10, 12, 14 were 45.94% in the cases of upper respiratory infection and 3/15, 6/17, 0/15, 1/16 respectively in the four controls groups. Condensied water samples from an air-conditioning system showed that Legionella Pneumophila was positive. Evidence showed that it was an outbreak resulting from LDB serogroup 9 and 12, accompanied by upper respiratory infection related to air-conditioning system contaminated by LDB. This was the first report Lp infection associated with an air-conditioning system in Cbina.