南京地区组织胞浆菌感染的流行病学调查

Investigation on the Epidemiology of Histoplasma capsulatum Infection in Nanjing District

用组织胞浆菌素(Histolyn-CYL,ALK/Berkeley Laboratories,美国)和PPD在南京市调查了292例当地居民或留居者,发现组织胞浆菌素皮试49例(16.78%)阳性,阳性皮肤反应直径为5.0～23.0(9.5±4.2)mm,其中正常人阳性率为15.10%,肺部疾病病人阳性率为17.74%;PPD皮试阳性率为56.16%,阳性反应直径为5～50(14.2±4.7)mm,其中正常人为59.43%,肺部疾病病人为54.30%;两种皮试均为阳性者有8.90%,组织胞浆菌素皮试阳性而PPD皮试阴性者为7.88%。结果表明南京地区存在组织胞浆菌人群感染。

Two hundred and ninety - two permanent or temporary residents in Nanjing district were tested with histoplasmin (Histolyn- CYL, ALK/Berkeley Laboratories, USA)and PPD. Forty- nine (16.78 %) subjects reacted to histoplasmin with 5.0 - 23.0(9.5±4.2)mm induration. Postive reaction rate among people without pulmonary diseases (normal group) was 15.10% comparing to 17.74% to patients with pulmonary diseases. Positive reaction to PPD with 5～50(14.2±4.7)mm induration was 56.16 %, with 59.43 % in normal group and 54.30 % in patients with pulmonary diseases while 8.90 % subjects reacted to both histoplasmin and PPD. 7.88 % of the research subjects reacted to hitoplasmin but not to PPD. Result suggested that there was herd infection of Histoplasma capsulatum in Nanjing district.