高血压与糖尿病慢性并发症

Hypertension and Diabetic Complication in Chinese Diabetic Patients

分析了５７７例ＮＩＤＤＭ患者中高血压的检出率及其对糖尿病并发症影响。５７７例中正常血压（＜１８．７／１２．０ｋＰａ）２９１例，轻度高血压（１８．７～２１．３／１２．０～１３．２ｋＰａ）１２２例，中度高血压（２１．３～２４．０／１３．３～１４．７ｋＰａ）８１例，重度高血压组（＞２４．０／１４．７ｋＰａ）４１例。４２例正在服降压药的血压正常者单独分组。高血压组的糖尿病患者视网膜和肾脏并发症的发生率明显高于血压正常组，且神经、视网膜和肾脏并发症的程度更严重。重度高血压组的患者中，这三种并发症的发生率分别达到５９％、６０％和３２％。正常眼底的糖尿病患者血压明显低于有视网膜病变组。无神经病变患者的血压值明显低于有神经病变组。高血压组的平均心率、尿白蛋白明显高于无高血压组，而前者心率变异值明显低于后者。逐步回归分析显示，收缩压是微血管病变的独立的危险因素。结论：必须加强糖尿病合并高血压检测和治疗。

The associations between hypertension(HP) and diabetic complications (DC) were investigated on 577 NIDDM.The patient with HP was 49 6%.The age,duration,heart rate,urine albumin excretions rate were higher significant differences in the HP group than without one.There were a higher incidence rate of complication on neuropathy,retina and kidneys in the HP group,and degree of serious was following with blood pressure.When the blood pressure was over 24 0/14 7 kPa the incident rate were 59% of neuropathy,60% of proliferative retinopathey and 32% of kidney.There were no significant differences in BMI,blood glucose,HbAlc,TC,TG,HDL C.The results of the step regression analysis showed that the systolic blood pressure was an independent risk factor for capillaropathy.The results suggested which must be more attention to treat and prevent DC with HP.