乳腺癌患者术后生活质量与焦虑、抑郁情绪的相关性分析

Correlation analysis of anxiety,depression and quality of life in patients with breast cancer

目的探讨乳腺癌患者术后生活质量与焦虑、抑郁情绪的相关性,为临床护士开展心理护理提供依据。方法采用欧洲癌症研究与治疗组织研制的生活质量核心量表(QLQ-C30)、Zung焦虑自评量表(SAS)和Zung抑郁自评量表(SDS)分别测评147例乳腺癌患者的生活质量及其焦虑和抑郁状况,并分析其相关性。结果乳腺癌患者术后QLQ-C30评分中的躯体功能、角色功能、情绪功能、认知功能、社会功能以及总体健康状况分别与SAS评分和SDS评分呈负相关,而症状维度与SAS评分和SDS评分呈正相关(均P<0.05)。结论乳腺癌患者术后焦虑、抑郁情绪越严重,其生活质量越差。提示临床护士应对其进行相应的心理辅导,提高患者的生活质量。

Objective To investigate the correlation between anxiety, depression and quality of life in patients with breast cancer after operation, to offer strong evidences to the clinical practice of mental nursing. Methods The life quality and mental state of 147 patients were respectively evaluated with Chinese version of the European organization for research and treatment for patients of cancer （EORTC QLQ-C30）, Zung self-rating anxiety scale （SAS） and Zung self-rating depression scale （SDS）, and their relationship was analyzed. Results All the dimensions of QLQ-C30, including physical function, role function, emotional function, cognitive function, social function and global health, were negatively correlated with the score of SAS respectively in breast cancer （all P 〈 0.05）. There were negative correlations between all the dimensions of QLQ-C30 and the score of SDS respectively in breast cancer too （all P 〈 0.05）. Conclusion Anxiety and depression were strongly associated with poor quality of life in breast cancer patients. The clinical nurses should provide psychological services to patients to improve their quality of life.