茶色素与诺衡治疗高血脂、高纤维蛋白原血症的对比研究

Tea Pigment and Lopid for Hyperlipidemia and Hyperfibrinogenemia:Clinical Comparative Study of Curative Effects

用茶色素与诺衡治疗３９１例高血脂或伴有高纤维蛋白原的患者，随机分成两组，茶色素组１９６例，服茶色素胶囊０２５ｇ，每日３次；诺衡组１９５例，服诺衡胶囊０６ｇ，每日２次。疗程为１月，服药前、后测定血脂、纤维蛋白原。服茶色素１月后，血清胆固醇（Ｃｈ）、甘油三脂（ＴＧ）、低密度脂蛋白胆固醇（ＬＤＬ－Ｃ）、纤维蛋白原（Ｆｂｇ）分别下降２８％，６３６％，３４５％，５２９％，高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）上升３７５％；总有效率为Ｃｈ９０３％，ＴＧ９６％，ＬＤＬ－Ｃ９２６％，ＨＤＬ－Ｃ８７７％，Ｆｂｇ９３８％。两药治疗高血脂症疗效差异无显著性（Ｐ＞００５）；降Ｆｂｇ的效果差异有高度显著性（ｔ＝３５０７，Ｐ＜００１）。副作用发生率茶色素为３１％，诺衡组２７８％，差异有高度显著性（ｔ＝８４３６，Ｐ＜０００１）。茶色素治疗高血脂、高纤维蛋白原血症有确切的疗效，无毒副作用。

o compare the effects of taa pigment and lopid for hyperlipidemia and hyperfibrinogenemia,the patients were randomly divided into two groups:①tea pigment group (TP,n=196),tea pigment capsules(125mg in each) 250mg were taken three times a day; ②Lopid capsules group(n=195) lopid capsules 600mg were taken twice a day. Blood lipid and fibrinogen were detected before and after administration for one month.Compared with lopid group,the levels of serum cholesterol(CH),triglyceride(TG), low density lipoprotein cholesterol (LDL-C),fibrinogen(Fbg) decreased 28%,636%,345%,529% respectively,their total effective ratio were 903%,96%,926%,877%,938% respectively in tea pigment group, there were no side effects occurred.It suggests that tea pigment is an ideal drug for the midde-aged and old-aged people to prevent and treat cardiocerebrovascular diseases.