高原肺水肿患者治疗前后血液流变性的变化

THE HEMORHEOLOGIC CHANGES OF PATIENTS WITH HIGH ALTITUDE PULMONARY EDEMA BEFORE AND AFTER TREATMENT

对１２例高原肺水患者在治疗前和临床治愈后，进行了（全血粘 度高切、低切）、Ｐ（血浆粘度）、（全血还原粘度）、ＨＣＴ（红细胞压积）、ＰＦＣ（纤维蛋 白原）、ＲＥＴ（红细胞电泳时间）、ＩＲ（红细胞刚性指数）、ＶＡＩ（血细胞聚集指数）、ＥＳＲ （血沉方程Ｋ值）等１０项血液流变学指标检测。结果经治疗痊愈后与治疗前的血 液流变学指标有很大的变化，ＰＦＣ、ＩＲ和 ＲＥＴ差异显著（Ｐ＜０、０５或 Ｐ＜０． ０１）。ＨＣＴ、ＶＡＩ、ＥＳＲ的差异则无显著意义（Ｐ＞０．０５）。认为，血液流变学指标变化 与高原肺水肿有一定关系，对高原肺水肿有一定关系，对高原肺水肿患者的病情判 断和治疗有参考价值。

Hemorheologic parameters such as Whole blood viscosity (b), plasma viscosity (p), reduced blood viscosity , hematocrit (HCT), fibrionogen (PFC), RET, IR, ESR and blood cell aggregation coefficient (VAI) were determined in 12 cases of patients with high altitude pulmonary edema before and after treatment. The results showed that parameters were changed and there were increasing differences for b, PFC, IR and RET(p<0. 05 or P<0. 01), differ-ences in HCT VAT. ESR (p>0. 05). The authors consider that the parameters of the hemorheological changes are dependent on high altitude pulmonary edema, and are useful for diagnosis and treatment of that disease.