38例川崎病的临床诊断、实验室检测分析

Diagnosis and analysis of laboratory testing to Kawasaki disease

目的根据川崎病(Kawasaki Disease,KD)临床特征、诊断、实验室检测分析,探讨提高临床诊断、治疗水平的方法。方法回顾我科2001年1月～2008年1月收治38例KD进行总结分析。结果33例KD治愈,5例伴发冠状动脉病变者随访6个月后恢复正常。结论1)KD伴有低钠血症患者存在重度炎症,因此在临床上要积极抗炎治疗;2)血浆D-二聚体(D-dimer)的检测可用于川崎病的早期辅助诊断还提示抗凝治疗在整个疾病的治疗中都是必要的;3)KD发生时免疫系统过度活化,所以强调发病10天以内应用丙种球蛋白(IVIG)效果较好。

Objective According to Kawasaki disease （KD） clinical features,diagnosis,analysis of laboratory testing to improve clinical diagnosis and treatment. Methods 38 cases of KD were treated from January 2001 to January 2008 at my subjects and were analyzed. Results KD associated with the risk factors for coronary artery lesions were analyzed. Conehmions 1） KD patients with hyponatremia existing severe inflammation, it should be clinically active anti-inflammatory treatment; 2）Plasma D-dimer （D-dimer）testing can be used for early diagnosis of Kawasaki disease and anticoagulant therapy in the treatment of diseases is necessary;3）KD patients with excessive activation of the immune system are stressed application gamma globulin （IVGG） better in 10 days.