基于OPENGL的蛋白质相互作用可视化研究

Visualizing Protein-Protein Interaction Based on OpenGL

蛋白质-蛋白质相互作用可视化研究是蛋白质组学中的重要研究内容,是生命科学研究的重要前沿课题之一。采用改进的关键词字典模式匹配算法从生物医学文献中提取蛋白质-蛋白质相互作用信息,基于OpenGL图形接口技术,根据二次方程对象渲染球体,运用分层插值逼近法使三维空间坐标点近似分布于球面,采用可视化知识表示法,将蛋白质-蛋白质相互作用信息以网络图方式在三维空间上立体显示。

The protein-protein interaction＇s visualization is a quite meaningful topic in protein science. It can help us to know if there are relationships among numerous proteins. Keywords dictionary pattern match algorithm was used to extract the protein-protein interaction information from the biomedical literatures. Based on the OpenGL graphics interface technology and stratified interpolation approximation method, the three dimensional coordinates of the points were approximately distributed on the ball surface with the approach of quadratic equation object rendering the ball. With the method of visual knowledge representation, the interaction relationship among the proteins was shown in the three dimensional space by the way of networks.