喉癌组织中CD146表达与微血管和淋巴管计数的关系
被引量：2
摘要
CDl46（anti—adhesion molecule）是一种单链跨膜糖蛋白，属于免疫球蛋白超家族成员。近年近发现CD146表达水平与恶性肿瘤进展、肿瘤血管生成、转移发生及预后密切相关。肿瘤组织微血管（microvessel，MV）密度和淋巴管（lymph vessel，LV）密度是判断恶性肿瘤进展、转移或复发及预后的客观指标，其意义可能仅次于淋巴结转移。采用EnVision和SP免疫组化法研究喉鳞状细胞癌（简称喉癌）组织中CD146表达水平及MV和LV计数，探讨它们的临床病理意义及在喉癌中相互关系。
出处
《中国耳鼻咽喉头颈外科》
北大核心
2009年第7期389-390,共2页
Chinese Archives of Otolaryngology-Head and Neck Surgery
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