三七通舒胶囊预防脑梗死复发的临床观察及对血液流变学的影响

Observation of sanqi shutong capsule preventing cerebral infarct recurrence and the effect of hemorheology

目的与阿司匹林肠溶片对照,评价三七通舒胶囊预防脑梗死复发的有效性及安全性以及对血液流变学的影响。方法100例脑梗死患者随机分为两组,治疗组给予三七通舒胶囊,对照组口服阿司匹林肠溶片。随访1年,观察脑梗死复发率及血液流变学变化。结果治疗组中有7例发脑梗死,对照组中有6例发脑梗死。两组患者脑梗死复发率无明显统计学差异;两组患者治疗前后血液流变学指标均有改善,但三者之间比较无明显差异。结论三七通舒胶囊与阿司匹林相比均能改善血液流变学指标,具有相同的预防脑梗死复发的作用,但前者消化道症状更轻微。

Objective Assessed efficacy and safety of sanqi shutong capsule preventing cerebral infarct recurrence and the effect of hemorheology compared with aspirin enteric-coated tablets. Methods 100 patients with cerebral infarct ware assigned to two groups randomly. Study group was treated with sanqi shutong capsule and control was treated with aspirin enteric-coated tablets. Observed the recurrence rate of cerebral infarct and change of hemorheology for one year. Results There were 7 cases of relapsed cerebral infarction in study group and 6 cases in control group. Two groups had no differences in recurrence rate of cerebral infarct and change of hemorheology ~ Conclusions Sanqi shutong capsule could improve the indexes of hemorheology compared with aspirin enteric-coated tablets. Sanqi shutong capsule had similar efficacy of preventing cerebral infarct recurrence with aspirin enteric-coated tablets and had more mild digestive tract symptoms.