呼吸机相关肺炎20例致病菌和药敏分析

Distribution and bacterial susceptibility analysis of ventilator-associated pneumonia

目的探讨呼吸机相关肺炎（VAP）的致病菌分布及对抗菌药物的敏感性。方法对某院呼吸科20例VAP患者的病原菌及药敏试验进行分析。结果20例患者支气管分泌物细菌培养获得致病菌42株，其中革兰阴性杆菌占71．4％，革兰阳性球菌占16．7％，真菌占11．9％。结论VAP感染以革兰阴性杆菌为主，并且耐药率较高，在治疗VAP时应重视病原菌的培养，以便根据药敏结果合理使用抗菌药物。

Objective To investigate the characteristics of pathogens and bacterial susceptibility in the patients with ventilator-associated pneumonia （VAP）. Methods The clinical characteristics of aetiological germ and bacterial susceptibility in 20 patients with VAP who were treated in the hospital department of respiratory medicine were analyzed. Results 20 patients with bronchial secretions cultured bacteria was 42. It showed that the isolating rate of gram-negative bacilli（GNB） ,gram-positive cocci and fungus was 71.4%, 16. 7% and 11.9% respeotively. Conclusions The main bacteri.um in patients with VAP was GNB,which exhibited higher resistance to common antibiotics. More attention should be paid to the cultivation of aetiological bacteria and selection of antibiotics in the treatment of VAP.