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罗红霉素对哮喘大鼠气道炎症及气道高反应性的影响

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摘要 目的观察罗红霉素对哮喘大鼠气道炎症、气道高反应性的影响。方法30只雄性SD大鼠随机分组和建模,罗红霉素干预28天,检测气道反应性和支气管肺泡灌洗液中的IL-4、IL-5、IFN-γ。结果罗红霉素组气道反应性以及BALF中IL-4、IL-5低于哮喘组,有显著性差异;结论罗红霉素具有减轻哮喘大鼠气道炎症和气道反应性。
出处 《海峡药学》 2009年第7期62-65,共4页 Strait Pharmaceutical Journal
基金 浙江省科技厅资助基金(2006C33074) 温州市科技局资助基金(Y20070136)
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