期刊文献+

血管侵犯与结肠癌术后复发转移的相关性 被引量:4

下载PDF
导出
摘要 目的探讨血管侵犯与结肠癌术后复发转移的相关性。方法收集行根治性手术的结肠癌患者共136例,将入选病例的病理蜡块重新切片进行血管侵犯的检测。血管侵犯的部位分为壁内血管侵犯、壁外血管侵犯和壁内外血管均侵犯;血管侵犯的程度分为V0:无血管侵犯,V1:1~3条血管侵犯,V2:4~6条血管侵犯,V3:>6条血管侵犯,分析其与术后复发转移的关系。结果平均每例患者送检蜡块数为3.6块,全组血管侵犯阳性率为43.4%。术后总的复发转移率为23.5%,其中伴有血管侵犯组为40.7%,无血管侵犯组为10.4%。血管侵犯是结肠癌术后复发转移的独立不良预后因素(P=0.001),壁内血管侵犯、壁外血管侵犯、壁内外血管均侵犯3组术后复发转移率分别为35.0%,41.7%,46.7%,均高于无血管侵犯组(均P<0.05),但3组间术后复发转移率差异无显著性(均P>0.05)。V1,V2,V3血管侵犯术后复发转移率分别为29.2%,42.9%,57.1%,均高于V0,且V3组术后复发转移率较V1组高(均P<0.05)。结论血管侵犯是结肠癌术后复发转移的独立不良预后因素,血管侵犯越严重,患者术后复发转移的机会越高。
出处 《广东医学》 CAS CSCD 北大核心 2009年第8期1130-1133,共4页 Guangdong Medical Journal
  • 相关文献

参考文献10

  • 1RADESPIEL TROGER M, HOHENBERGER W, REINGRU BER B. Improved prediction of recurrence after curative resection of colon carcinoma using tree - based risk stratification [ J ]. Cancer, 2004, 100(5) : 958 -967.
  • 2LUI K K, ENJOJI M, INOKUCHI K. Venous permeation of colorectal carcinoma[J].Jpn J Surg, 1980, 10(4) : 284 -289.
  • 3CHAPUIS P H, DENT O F, BOKEY E L, et al. Adverse histopathological findings as a guide to patient management after curative resection of node - positive colonic cancer [ J ]. Br J Surg, 2004, 91(3) : 349 -354.
  • 4FUJITA S, SHIMODA T, YOSHIMURA K, et al. Prospective e-valuation of prognostic factors in patients with colorectal cancer undergoing curative resection [J]. J Surg Oncol, 2003, 84 (3) : 127 -131.
  • 5COMPTON CC. Pathologic staging of colorectal cancer: an advanced users, guide [ M ]. Lippincott : Williams & Wilkins, 2004: 150 - 162.
  • 6STERNBERG A, MIZRAHI A, AMAR M, et al. Detection of venous invasion in surgical specimens of colorectal carcinoma: the efficacy of various types of tissue blocks [ J ]. J Clin Pathol, 2006, 59(2) : 207 -210.
  • 7RADESPIEL TROGER M, HOHENBERGER W, REINGRUBER B. Improved prediction of recurrence after curative resection of colon carcinoma using tree - based risk stratification [ J ]. Cancer, 2004, 100(5) : 958 -967.
  • 8HORN A, DAHL O, MORILD I. Venous and neural invasion as predictors of recurrence in rectal adenocarcinoma [ J ]. Dis Colon Rectum, 1991,34(9) : 798 -804.
  • 9GUNTHER K, DWORAK O, REMKE S, et al. Prediction of distant metastases after curative surgery for rectal cancer[ J]. J Surg Res, 2002, 103(1): 68-78.
  • 10PETERSEN V C, BAXTER K J, LOVE S B, et al. Identification of objective pathological prognostic determinants and models of prognosis in Dukes, B colon cancer[J]. Gut, 21302, 51(1): 65-69.

同被引文献41

引证文献4

二级引证文献48

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部