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结缔组织生长因子和转化生长因子-β1与慢性心力衰竭的关系

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摘要 随着人们生活水平的提高，心血管疾病已成为严重威胁人类健康的主要疾病。慢性心力衰竭是各种心血管疾病发展的终末阶段，并与心肌纤维化密切相关。结缔组织生长因子（connective tissue growth factor，CTGF）和转化生长因子-β1（transforming growth factor—β，TGF-β1）是两种促成纤维分裂和胶原沉积的细胞因子，与多种器官的纤维化密切相关。现就CTGF、TGFβ1与慢性心力衰竭及心肌纤维化的关系做一综述。
作者 刘国红 孙尧 朱莉军
机构地区 华北煤炭医学院附属医院老年病科
出处 《中国综合临床》 2009年第8期895-896,共2页 Clinical Medicine of China
关键词 慢性心力衰竭 结缔组织生长因子 转化生长因子 心肌纤维化
分类号 R285.5 [医药卫生—中药学]
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参考文献9

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中国综合临床
2009年 第8期

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