硅杂六元环化合物的合成

Synthesis of Six-Membered Silacycles

本文综述了环上只含有一个硅原子的硅杂六元环化合物在有机合成方法学方面的进展。介绍了通过α,ω-双金属试剂的关环反应、硅烯参与的[4+2]环加成反应、生成C—Si键的关环反应、生成C—C键的关环反应、硅杂环扩环反应等来合成硅杂六元环化合物,总结了硅杂环己烷、硅杂环己烯以及硅杂环己二烯等不同结构化合物的常见合成方法,为促进硅杂六元环化合物在有机合成化学和材料科学方面的进一步应用提供了基础。

Progress in synthetic methodology for six-membered silacycles with one silicon atom in the ring is introduced. Six-membered silacycles are synthesized by the following methods： ring closure by silylation of α, ω- dimetallic compounds, [4 ＋ 2] cycloaddition reaction involving silenes, ring closure by C--Si bond formation, ring closure by C--C bond formation, ring expansion reaction of smaller silacycles, etc. A variety of silacyclohexane, silacyclohexene and silacyclohexadiene derivatives are readily accessible by these transformations. Further application of six-membered silacycles in organic chemistry and materials science can be envisioned.