六耳铃化学成分研究

Studies on the Chemical Constituents of Blumea laciniata

目的：研究六耳铃的化学成分。方法：采用柱色谱技术，分离六耳铃醇提物的乙酸乙酯萃取部位的化学成分；根据光谱分析和文献对照的方法鉴定分离所得化合物的结构。结果：分离并鉴定了5个化合物，分别为原儿茶酸（1）、香叶木素（2）、芹菜素（3）、4-羟基-3，5-二甲氧基苯甲酸（4）、东莨菪素（5）。结论：化合物1～5均为首次从该植物中分离得到，亦首次从艾纳香属植物中分离得到。

Objective： To study the chemical constituents of Blumea laciniata. Methods： The chemical constituents of the ethyl acetate fraction of ethanol extract from Blumea laciniata were isolated with column chromatographic techniques. The structures of the isolated compounds were elucidated by spectroscopic analysis and comparison with their published datas. Results ： Five compounds were isolated and identified as ： protocatechuic acid （ 1 ）, chrysoeriol （ 2 ） , apigenin （ 3 ） , 4-hydroxy-3,5-dimethoxbenzoic acid （ 4 ）, scopolet （5）. Conclusion： Compounds 1 -5 are isolated from this plant for the first time, and also obtained from this genus for the first time.