摘要
目的评价国内针灸治疗椎-基底动脉供血不足综合征(VBI)的临床疗效及安全性。方法搜集相关随机对照试验文献,筛选合格研究共8项,并对其评分进行质量评价,运用Meta分析、漏斗图分析等方法统计相关数据,得出综合结论。结果8篇文献评分均在3分以下,文献质量较低;Meta分析合并OR=4.36,95%可信区间为2.88～7.45,菱形位于垂线右侧(Z=6.33,P<0.00001),表明针灸对VBI的治疗效果优于对照组;漏斗图左右不对称,呈偏态分布,提示可能存在发表性偏倚。结论单纯从统计结果分析,可认为针灸治疗本病疗效基本肯定,但研究质量低是影响该系统评价结论的最主要因素。
Objective To assess the effectiveness and safety of acupuncture and moxibustion for treatment of vertebrobasilar insuffciency （VBI）. Methods Randomized controUed trails （RCTs） of VBI treated by acupuncture and moxibustion were collected. 8 RCTs were included and assessed. The data was statistically analyzed by Meta-analysis and Funnel plot analysis. Result 8 RCTs were all trails of low methodological quality. Meta-analysis indicated after combination OR=4.36, confidence interval of 95% was 2.88-7.45. The rhombus was located at the right side of the medium line （Z=6.33, P〈0.00001）, the therapeutic effect in the treatment group was significantly higher than that of the control group. Funnel plot analysis showed skew distribution, indicating the publication bias. Conclusion The Meta-analysis review showed that acupuncture and moxibustion is effective for VBI. However the evidence is not strong due to the general low methodological quality.
出处
《中国中医药信息杂志》
CAS
CSCD
2009年第8期107-109,112,共4页
Chinese Journal of Information on Traditional Chinese Medicine
基金
湖北省2006年度中医药中西医结合科研课题(2006-36)
