鼻咽癌颈淋巴结转移灶放疗、热疗的观察及护理

Effect of radiotherapy combined with hyperthermia on cervical lymph node metastasis of nasopharyngeal carcinoma and nursing

目的:比较放疗配合热疗在治疗鼻咽癌颈淋巴结转移灶中的作用。方法:对我科收治的46例有颈部淋巴结转移癌≥4cm的鼻咽癌患者,随机分成两组,观察组26例,采用放疗+热疗方法治疗;对照组20例,采用单纯放疗方法治疗。结果:放疗结束时,观察组、对照组颈部淋巴结全消率分别为61.5%、30.0%,经χ2检验,P<0.05,有统计学意义。结论:对颈部较大淋巴结转移的鼻咽癌患者,放疗配合热疗有明显的互补和增效作用,做好热疗过程的护理,可减少热疗不良反应,增加治疗肿瘤的敏感性,以改变患者的生存质量,提高生存率。

Objective： To investigate the effects of radiotherapy combined with hyperthermia on cervical lymph node metastasis of nasopharyngeal carcinoma and the role of nursing. Methods： Forty-six patients with enlarged cervical lymph node （diameter≥4 cm） due to metastasis of nasopharyngeal carcinoma undergoing treatment were randomly assigned into group A （ n = 26） and group B （ n = 20）, patients in group A were treated with radiotherapy and hyperthermia, patients in group B were treated with radiotherapy, the patients were received good nursing, and the effects were studied and nursing care was summarized ; χ2 test was used for the analysis of qualitative data, and P 〈 0.05 was considered significant. Results： After therapy, the resolution of enlarged cervical lymph nodes in group A and B was 61.5% and 30% respectively, the difference between the two groups was significant （ P 〈 0.05 ）. Conclusion： Hyperthermia has marked adjunctive effects on the radiotherapy of cervical lymph node metastasis of nasopharyngeal carcinoma and may enhance the general effect; delicate nursing may reduce adverse reactions of hyperthermia, increase sensitivity of carcinoma to radiotherapy, improve life quality , and enhance survival rate.