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基于不同饲料的洋虫水提液对小鼠的抗衰老作用 被引量:4

Anti-senile effects of water extraction of Martianus dermestoides (Coleoptera:Tenebrionidae) feeding different foods on aging mice
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摘要 为了评价洋虫Martianus dermestoides成虫和幼虫水提液的抗衰老作用,用高级饲料红花、枸杞、大枣、核桃仁的混合饲料)、大米、麦麸饲料饲养洋虫成虫和幼虫,并用幼虫水提液对D-半乳糖致衰老小鼠灌胃,测定小鼠血清中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)和过氧化氢酶(CAT)的活力及丙二醛(MDA)含量。结果表明:3种饲料饲养的洋虫成虫水提液均能提高小鼠血清中SOD,GSH-Px和CAT活力(P<0.05或P<0.01),且显著降低MDA含量(P<0.05);高级饲料组作用优于大米及麦麸饲料组,但三者差异不显著。高级饲料饲养组,其幼虫水提液对小鼠血清中SOD和CAT活力作用显著强于成虫水提液(P<0.05);对GSH-Px活力及MDA含量影响差异不显著。揭示洋虫成虫和幼虫水提液均有一定的抗氧化作用,是一种有效的抗衰老保健食品,且幼虫抗氧化作用优于成虫,饲料种类对洋虫的抗氧化作用无显著影响。 This article reported the anti-senile effect of water extraction of Martianus dermestoides adults and larvae by testing the activities of SOD, GSH-Px and CAT and MDA content in blood serum of mice. Water extraction was distilled from adults and larvae of M. dermestoides which were separately reared by the advanced forage (consisting of safflower, medlar, Chinese date and Juglans regia nuts) , rice and wheat bran. We use water extraction of M. dermestoides larvae to clystere the mice which were of a senile model established by injecting D-galactose. The results demonstrated that all the water extraction of M. dermestoides adults reared by three kinds of forage increased the activities of SOD, GSH-Px and CAT (P 〈 0.05 or P 〈 0.01 ) in blood serum of mice, and decreased the MDA content (P 〈0.05 ) ; the effect of the advanced forage group was stronger than the other two groups, but there were no significant differences among the three groups. SOD and CAT activities in blood serum of the mice which had been clystered with water extraction of M. dermestoides larvae were obviously higher than those of the adults, both reared by the advanced forage (P 〈 0.05 ) ; however, there were no significant differences between GSH-Px activity and MDA content. The results suggest that water extraction of both adults and larvae of M. dermestoides have antioxidant activity, amd M. dermestoides can be exploited as a kind of health food with anti-senile effect.
出处 《昆虫学报》 CAS CSCD 北大核心 2009年第7期820-824,共5页 Acta Entomologica Sinica
关键词 洋虫 超氧化物歧化酶 谷胱甘肽过氧化物酶 过氧化氢酶 丙二醛 抗衰老 Martianus dermestoides superoxide dismutase glutathione peroxidase eatalase malonaldehyde anti -senile
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