低频重复经颅磁刺激对脑外伤患者认知功能和功能独立的影响

Effect of low-frequency repetitive transcranial magnetic stimulation promotes recovery of cognitive function and functional independence in patients with traumatic brain injury

目的观察低频重复经颅磁刺激改善脑外伤患者的认知功能和功能独立的作用。方法将60例脑损伤患者按随机数字表法分为治疗组和对照组（各30例），均给予常规治疗。治疗组在此基础上应用低频重复经颅磁刺激治疗，连续治疗5d为1个疗程，疗程之间间隔2d，连续4个疗程。观察两组患者治疗前后Rivermead行为记忆评分（RBMT）和功能独立性评分（VIM）。结果两组患者治疗后RBMT评分（治疗组：17．72±5．69，对照组：16．86±4．82）和FIM评分（治疗组：75．19±16．55，对照组：59．86±15．27）均较治疗前（治疗组：13．97±4．37，对照组：14．25±4．51；治疗组：43．21±12．62，对照组：45．79±13．97）有明显改善，比较差异有统计学意义（P〈0．05）；两组治疗前后RBMT评分差值（3．68±2．06 vs2．71±1．17）和FIM评分差值（31．86±10．89vs18．71±11．17）比较差异也有统计学意义（P〈0．05）。结论低频重复经颅磁刺激对脑外伤患者认知功能和功能独立的改善有明显促进作用。

Objective To observe the effect of low-frequency repetitive transcranial magnetic stimulation in improving the memory function and quality of life of patients with traumatic brain injury. Methods Sixty patients with brain injury were randomly divided into the treatment group and control group. The patients in the control group received conventional treatments （including medications, acupuncture and exercise training）, and those in the treatment group were given additional low-frequency repetitive transcranial magnetic stimulation treatment. Scores of the Rivennead Behavioral Memory Test （RBMT） and Functional Independence Measure （FIM） were recorded before and after the treatments and compared between the two groups, Results The patients in both of the groups showed significant improvements in RBMT and FIM scores after the treatments （P〈0.05）. The improvements in RBMT and FIM scores after the treatments differed significantly between the two groups （P〈0.05）. Conclusion Low-frequency repetitive transcranial magnetic stimulation can significantly improve the cognitive function and functional independence of patients with traumatic brain injury.