肝癌患者红细胞免疫功能检测及评价

Detection and evaluation of erythrocyte immune function of patients with liver cancer

目的:研究肝癌患者红细胞免疫功能变化的规律。方法:采用郭峰法测定45例肝癌患者及45例正常对照人群的红细胞免疫功能。结果:肝癌患者红细胞免疫功能明显下降,红细胞C3b受体花环率(RBC-C3bRR)、肿瘤红细胞花环(RBC-CaR)显著低于正常对照组,而红细胞免疫复合物花环率(RBC-ICR)显著高于对照组(P<0.05)。结论:原发性肝癌患者存在红细胞免疫功能障碍,因此在免疫治疗中,应加强红细胞免疫功能的调节和恢复。

Objective：To explore the erythrocyte immune function in patients with liver cancer. Methods：Guo - Feng method was used to detect the erythrocyte immune function in 45 liver cancer patients and 45 normal controls. Results：RBC- C3bRR and RBC- CaR of patients with hver cancer were significantly lower than that of the normal control. REC - ICR of patients was higher than that of control. Conclusion ： Lower erythrocyte immune function is one of the important factors which affects the therapeutic effect of liver cancer. Evaluation of erythrocyte immune function is important to diagnosis and therapy of liver cancer.