中重度慢性阻塞性肺疾病患者6分钟步行试验及其相关因素分析

Correlation study of six minute walk test with FEV_1%,MMRC and SGRQ in patients with moderate-severe chronic obstructive pulmonary disease

目的:探讨中重度COPD稳定期患者6min步行试验(6MWT)与肺功能、呼吸困难及生活质量的相关性。方法:选取中重度COPD患者63例,进行6min步行试验并测定肺功能、呼吸困难评分(MMRC)、生活质量(SGRQ)等指标。结果:FEV1%、MMRC、SGRQ总评分及活动能力评分、社交心理影响评分与6min步行距离(6MWD)相关,多元逐步回归分析表明MMRC及活动能力评分与6MWD相关。结论:中重度COPD患者6MWD与MMRC、FEV1%及SGRQ相关。6min步行试验能反映中重度COPD患者的临床状况。

Objective： To discuss the relationship of six minute walk test with FEV1%, MMRC and SGRQ in patients with chronic obstructive pulmonary disease. Methods： Six minute walk test （6MWT）, pulmonary function, MMRC and SGRQ were detected in 63 patients who were diagnosed moderate to severe COPD. Results： FEV1%, MMRC and SGRQ were cor- related with the 6MWD. MMRC and SGRQ were correlated with 6MWD in step wise muhi-variate linear regression analysis. Conclusion： 6MWD has close relation with MMRC, FEV1% and SGRQ in the patients with moderate-severe COPD. 6MWT can reflect the clinical condition of COPD.