垂体后叶素治疗咯血患者引起低钠血症的临床分析

Clinical observation on hemoptysis patients with hypolphysin leading to hyponatremia

目的:探讨垂体后叶素在治疗咯血患者中引起低钠血症的机制、临床表现及防治方法。方法:对2000年1月～2008年10月因咯血在我科住院使用垂体后叶素静脉滴注引起低钠血症的46例患者进行回顾性分析。结果:46例患者中24例(52.17%)无临床症状,血清钠为(127±3)mmol/L。22例(47.83%)出现临床症状,恶心、呕吐、纳差20例(43.48%),头痛、乏力、表情淡漠、反应迟钝、嗜睡7例(15.22%),昏迷1例(2.17%)。结论:在使用垂体后叶素治疗咯血患者时,应注意观察病情变化,动态监测血清钠的浓度,注意低钠血症的发生,并予及时纠正,防止严重并发症。

Objective：To explore the mechanism,clinical characteristic and treatment of hemoptysis patients with hypophysin leading to hyponatremia. Methods：Retrospective analysis of the hemoptysis patients with hypophysin leading to hypanatremia of 46 hospitalized cases from January 2000 to October 2008 was made. Results：Of the 46 cases,24 （52.17%） were wihtout cinical symptom,the concentration of serum sodium was （127±3） mmol/L.22（47.83%）had clinical symptom, nausea, vomiting and decreased food appetite occurred to 20（43.48%）cases, headache, debilitation, apathia, torpidity, lethargy occurred to 7（15.22%） cases, coma occurred to 1 （2.17%） case. Conclusion：When the hypophysin is used in treatment of hemoptysis patients,the change of concentration of the serum sodium should be monitored at any time and attention should be paid to the occurrence of hyponatremia and serious complications.