瑞芬太尼+丙泊酚多学科手术麻醉效果评价

Remifentanil + Propofol anesthesia effect of multidisciplinary evaluation

目的:观察探索瑞芬太尼+丙泊酚在多学科手术麻醉中的应用效果。为短小手术提供最佳麻醉方法、麻醉药物和剂量。方法:将瑞芬太尼+丙泊酚静脉复合麻醉用于人工流产术、开胸引流术、开颅减压术、扁桃体切除术、骨科小手术等,观察术中血流动力学变化、麻醉诱导、手术、苏醒时间和定向力恢复、镇痛效果及术后不良反应发生情况。结果:瑞芬太尼+丙泊酚在多学科应用血流动力学、作用时间、镇痛效果、副作用发生率各组间无显著性差异,P>0.05。瑞芬太尼+丙泊酚三种剂量副作用对照A、B组与C组比较,P<0.05;A、C组与B组比较,P<0.05;镇痛效果B、C组与A组比较P<0.05。瑞芬太尼+丙泊酚组合,安全保障的最佳用药量分别为0.9～1.4μg/mg、1.9～2.2mg/kg。结论:瑞芬太尼+丙泊酚组合在多学科应用血流动力学干扰轻,作用时间理想,镇痛效果显著,副作用发生率低,不受体质、性别、年龄影响,适用于多学科手术麻醉。

Objective：Observation to explore remifentanil ＋ propofol an.esthesia in the muhidisciplinary in effect. For short surgical anesthesia to provide the best method and dose of narcotic drugs. Methods： The remifentanil ＋ propofol intravenous anesthesia for induced abortion, thoracic drainage, decompression craniotomy, tonsillectomy, orthopedic and other minor operation to observe the changes in hemodynamics, anesthesia induction, surgery, recovery time, and orientation recovery, analgesic effect and after the occurrence of adverse reactions. Rsults： Remifentanil ＋ propofol muhidisci- plinary application in hemodynamics, the role of time, the analgesic effect, the incidence of side effects among the three groups no significant difference, P〉0.05. Remifentanil ＋ propofol control side effects of three doses of A, B and C group comparison, P〈0.05; A, C group and B group, P〈0.05; analgesic effect of B, C group and A group P〈0.05. Remifentanil ＋ propofol combination of security best dosage of 0.9-1.4 μg/mg ,1.9-2.2 mg/kg.Conclusion： Remifentanil ＋ propofol combination in muhidisciplinary application of hemodynamic interference light, the ideal time, a significant analgesic effect, low incidence of side effects, free from physical, gender, age, apply to muhidisciplinary surgery