期刊文献+

厄贝沙坦联合胺碘酮治疗阵发性心房纤颤86例临床观察 被引量:3

原文传递
导出
摘要 目的探讨厄贝沙坦联合胺碘酮治疗阵发性心房颤动的临床疗效。方法将86例阵发性心房颤动的患者分为治疗组和对照组,均给予胺碘酮治疗,治疗组加用厄贝沙坦,疗程均为1年。比较两组治疗后第3、6、12个月的窦性心律维持率和治疗后第6、12个月的左心房内径。结果治疗后第3、6个月治疗组窦性心律的维持率分别为87%和80%,高于对照组的84%和71%,两组间比较差异无统计学意义(P〉0.05),而治疗后12个月后,治疗组的窦性心律维持率为77%,对照组为58%,两组间比较差异有统计学意义(P〈0.05)。治疗组治疗前、治疗后第6个月和第12个月的左心房内径分别为(39.8±1.4)mm、(38.3±1.9)mm、(37.5±1.6)mm;对照组为(38.7±1.7)mm、(38.7±1.7)mm、(39.8±1.5)mm,两组治疗12个月后左心房内径比较差异有统计学意义(P〈0.05)。结论厄贝沙坦联合胺碘酮治疗阵发性心房颤动,预防心房颤动复发的疗效显著优于单用胺碘酮,并有延缓左心房扩大的作用。
作者 曾庆华
出处 《临床内科杂志》 CAS 2009年第8期554-555,共2页 Journal of Clinical Internal Medicine
  • 相关文献

参考文献6

  • 1Healev J S,Morillo CA,Comaolly S J,el al.Role of the remfin-angioten.sin-aldosterone system in atrial fibrillation and cardiac remodeling.Curr Opin Cardio1,2004,20:31-37.
  • 2刘彤,李广平.左房扩大与心房颤动关系的研究进展[J].临床心电学杂志,2005,14(3):212-214. 被引量:49
  • 3Allessie M,Ausma J,Schotyen U,et al.Electrical,contractile and structural remodeling during atrial fibrillation.Cardiovasc Res,2002,54:230-246.
  • 4Madrid AH,Bueno MG,Rebollo JM,et al.Use of irhesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibriUation:a prospective and randomized study.Circulation,2002,106:331-336.
  • 5Vermes E,Tardif JC,Bourassa MG,et al.Enalapril decreases the incidence of atrial fibrillation in patients with left ventricular dysfunction:insight from the studies of left ventricular dysfunction (SOLVD) trials.Circulation,2003,107:2926-2931.
  • 6Uengk C,Tsai TP,Yu WC,et al.Use of enalapril to facilitate sinus rhythm maintenance after external cardioversion of long-standing persistent atrial fibrilation:Results of a propestive and controlled study.Eur Heart J,2003,24:2090-2098.

二级参考文献24

  • 1Kannel MB,Abbott RD,Savage DD,et al. Epidemiologic features of chronic atrial fibriUatin: the Framingham Study. N Engl J Med, 1982,306:1018~1022.
  • 2Petersen P,Kastrup J,Brinch K,et al. Relation between left a trial diameters and duration of atrial fibrillation. Am J Cardiol, 1987,60:382~384.
  • 3Keren G,Etzion T,Sherez J,et al. Atrial fibrillation and atrial enlargement in patients with mitral stenosis. Am Heart J, 1987, 114:1146~1155.
  • 4Vaziri SM,Larson MG,Benjamin E J,et al. Echocardiographic predictor of nonrheumatic atrial fibrillation: the Framingham Heart Study. Circulation,1994,89:724~730.
  • 5Pasaty BM,Manolio TA,Kuller LH,et al. Incidence of and risk factors for atrial fibrillation in older adults. Circulation, 1997,96: 2455~2461.
  • 6Tsang TS,Barnes ME,Bailey KR,et al. Left atrial volume: im portant risk marker of incident atrial fibrillation in 1655 older men and women. Mayo Clin Proc,2001,76(5):467~475.
  • 7Lester S J,Ryan EW,Schiller NB,et al. Best method in clinical practice and research studies to determine left atrial size. Am J Cardiol, 1999,84:829~832.
  • 8Sanfilippo AJ,Abascal VM,Sheehan M,et al. Atrial enlargement as a consequence of atrial fibrillation:a prospective echocardiographic study. Circulation,1990,82: 792~797.
  • 9Suarez GS,Lampert S,Ravid S,et al. Changes in left atrial size in patients with lone atrial fibrillation. Clin Cardiol,1991,14 (8): 652~656.
  • 10Villecco AS,Pilati G,Bianchi G,et al. Left atrial size in parox ysmal atrial fibrillation: echocardiographic evaluation and follow up. Cardiology, 1992,80(2):89~93.

共引文献48

同被引文献24

引证文献3

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部