血糖四分体的新主角——血糖波动性

Glycemic variability:new concept of unified glucose concept.

血糖波动性成为血糖四分体的一个组分。长期血糖波动可以增加氧化应激,促进糖尿病微血管病变的发生。血糖波动与糖尿病大血管病变的关系有待进一步研究。CGMS有助于监测血糖波动,适用于对脆性血糖的患者或对低血糖感知下降的患者调整治疗。在T2DM患者中即使总体血糖控制较为理想,也需要采取有效措施降低血糖波动。选择合适的治疗策略是控制血糖波动的关键。

The glycemic variability is one component of unified glucose tetrad concept. The long-term glycemic fluctuation may enhance the oxidative stress reaction, which can promote the development of micro vascular complications. The relationship between the glycemic variability and the CVD deserves further investigation. CGMS is helpful to monitor the glucose fluctuation especially in those with fragile diabetes and no symptom hypoglycemia. The suitable regime is the key point to control glycemic variability,even after the desired HbA1 c target is attained.