振动法对外敷七厘散动物模型骨折愈合的病理研究

Effects of Qili San on fracture healing by the vibration method in animal model

目的探讨振动法对中药七厘散外敷动物骨折愈合的促进作用,为临床提高骨折康复质量提供依据。方法将家兔随机分为4组,1组为对照组,2～4组分别在骨折后1天、2天、3天给予中药七厘散外敷包扎,配合低频率间歇振动,骨折前及骨折后1周、2周、3周拍X线片,观察骨痂形成情况,3周末处死,行弯曲试验及病理切片检查。结果3、4组经振动后最大载荷平均增加了20%;最大弯矩平均增加了39%;组织学愈合良好,软组织血供丰富;三周末骨痂形成率平均较对照组增加了21.4%。结论采用中药七厘散外敷包扎配合小型振动仪间歇振动可有效促进骨折愈合速度和质量;振动介入以骨折后2天、3天为佳。

Objective To discuss the vibration method for promoting of herbal healing medicine Qili San to external use in order to promote quality of fracture rehabilitation provides gist. Methods The rabbits were randomly divided into four groups, groups 1 was the control group, group 2-4 were given Qili san to dressing of external use, separated in the first day, the second day, the third day after fracture, with low frequency intermittent vibration, before fracture and the first week, the second week and the third week after fracture will be observed bone formation by x-ray, the third weekends executed, then do bending test and pathological biopsy. Results group 3-4 were increased averagely by percent 20 by largest loads after vibration; largest carved rules is increased averagely by percent 3p. Histological healed well, The blood supply of parenchyma is richness. Three weekends bone formation rate was increased averagely by percent 21.4 than the control group. Conclusion Chinese medicine Qili san extral dressing with smaller model vibration intermittent vibration can promote effectively speed and quality of fraction healing; The second day, the third day after fraction intervent vibration is better.