血管内皮生长因子与子宫内膜透明细胞癌预后相关性研究

The correlated study on VEGF and the prognosis of uterine endometrial dear cell carcinoma

目的研究子宫内膜透明细胞癌ECCC（uterine endometrial clear call carcinoma，ECCC）组织中血管内皮生长因子（vascular endothelial growth factor，VEGF）和血小板源性生长因子（platelet-derived endothelial cell growth factor PD—ECG／TP）的表达，从肿瘤新生血管的形成方面来探讨ECCC的预后相关因素。方法应用免疫组化法检测24例ECCC组织中VEGF、TP的表达，根据VEGF表达情况分成高表达组和低表达组，分析两组患者的生存差异。结果在ECCC组织中，VEGF／TP均有较高的表达，两组患者的生存差异有统计学意义。结论低表达组患者的生存时间长于高表达组。

Objective To determine and analyze the relationship between VEGF/TP expression and ECCC patients＇survival time. Methods 24 cases of ECCC were analyzed by immunohistechemistry. We separa- ted the patients into high and Low expressions of VEGF group Results low or high expressions of VEGF and TP has a significant influential difference for the patients＇ survival time. Conclusion There is a close relationship between VEGF expression and prognosis of ECCC