甲状腺髓样癌的诊断和治疗(附16例报告)

Report of diagnosis and treatment of medullary thyroid carcinoma (16 cases)

目的探讨甲状腺髓样癌患者的临床特点、诊断和治疗原则。方法回顾性分析2001年6月～2008年6月该科治疗的16例甲状腺髓样癌患者的临床资料。结果全组病例均经病理证实为甲状腺髓样癌,3例患者合并颈淋巴结转移。15例患者施行甲状腺癌根治手术,1例患者行姑息性切除术。术后监测血清降钙素,发现1例复发转移,再次手术。结论甲状腺髓样癌术前确诊困难,根治性手术切除是最主要治疗方法,术后监测血清降钙素能及早发现局部复发和转移。

[Objective] To study the clinical features, diagnosis and treatment of medullary thyroid carcinoma. [Methods] A retrospective analysis was made on 16 cases of medullary thyroid carcinoma surgically treated in our department from 2001.6 to 2008.6. [Results] The diagnosis of MTC in the 16 patients was confirmed by pathology. 3 cases of them, had lymph node metastases. 15 cases were fulfilled by radical surgery, and 1 case was fulfilled by partial thyroidectomy. All the patients measured plasma caleitonin after initial operation. Regional recurrence and metastases were found in 1 case and had reoperated. [Conclusions] MTC is difficult to be diagnosed preoperatively, radical surgery is the major treatment. Plasma ealeitonin measurement after initial operation ean early detect regional recurrence and metastases.