局部晚期宫颈癌新辅助化疗22例临床分析

Locally advanced cervical cancer neoadjuvant chemotherapy for clinical analysis of 22 cases

目的观察局部晚期宫颈癌新辅助化疗的疗效及应用价值。方法宫颈癌22例中Ⅰb期(巨块型直径≥4cm)10例,Ⅱa期6例,Ⅱb期6例,均采用VBP方案化疗,根据近期疗效予以进一步手术或放疗。结果近期有效率90.9%(20/22),其中Ⅰb期1例,Ⅱa期1例,经两周期化疗后属病理完全缓解,完全缓解率9%,化疗结束后手术切除率90.9%。结论宫颈癌术前化疗使癌灶缩小,提高了手术切除率及患者的生存质量。

Objective Observation of locally advanced cervical cancer neoadjuvant chemotherapy efficacy and application value. Methods 22 cases of cervical cancer in phase Ⅰb （ Huge diameter ≥ 4 cm） 10 cases, Ⅱa period of six cases, Ⅱb period of six cases, are VBP chemotherapy, according to short-term effect will be further surgery or radiotherapy. Results Recently, 90. 9% efficiency （20/22）, which Ⅰb Phase 1 cases, Ⅱa Phase 1, after the two cycles of chemotherapy is a pathological complete remission, complete remission rate of 9% and chemotherapy after the surgical resection rate of 90. 9%. Conclusion So cervical cancer preoperative chemotherapy reduced, increased the resection rate and quality of life of patients.