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尿钠肽测定观察肾衰竭患者心功能不全变化 被引量:2

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摘要 目的通过尿钠肽(BNP)测定,明确肾衰竭患者因水钠潴留、贫血、血压控制不佳等因素,造成左心衰竭。临床上观察透析前后尿钠肽变化。方法38例患者透析前及气急、胸闷、呼吸困难改善后透析,静脉各采血0.5ml加入DTA(乙二胺四乙酸)抗凝剂。采用美国Blosit(Triagc)心力衰竭测试仪测定对照。结果38例肾透析患者呼吸困难患者31例尿钠肽明显增高。最高>5000μg/L,透析前尿钠肽(2480.5±1270)μg/L,透析后尿钠肽(1449.8±788.4)μg/L,P>0.05。结论尿钠肽是反映左心功能不全地敏感特异性指标。可区分心源性呼吸困难与非心源性呼吸困难。使诊断尿毒症心力衰竭变得客观化,就像诊断肾功能衰竭,测定血肌酐、尿素氮一样直观。慢性肾功能衰竭尿钠肽也可增高。该检测在临床上及时,快速容易诊断尿毒症心功能不全方法。
作者 任根梅
出处 《中国实用医药》 2009年第23期87-88,共2页 China Practical Medicine
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参考文献2

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