医务人员非酒精性脂肪肝患病调查及相关因素分析1655例

A nonalcoholic fatty liver survey of 1655 medical staffs and analysis of relative factors

目的:了解医务人员非酒精性脂肪性肝病(NAFLD)的患病状况,并调查分析相关因素.方法:收集医院职工体检者1655例,根据体检结果以及肝脏B超结果分为2组,NAFLD组(n=230)和非NAFLD组(n=1425),比较分析NAFLD的相关因素.结果:NAFLD总体患病率13.9%,男性占20.7%,女性占10.8%,男职工NAFLD患病率明显高于女职工(χ2=28.70,P<0.001);其中50-59岁男性医生NAFLD患病率明显高于其他年龄段及工种人员;活动减少、在外就餐、高脂饮食是导致NAFLD的主要不良生活习惯.结论:代谢综合征、肥胖、高血糖与NAFLD高度相关,体质量指数增高有助于预测NAFLD的风险.

AIM： To study the prevalence of nonalcoholic fatty liver disease （NAFLD） among the medical staffs and to investigate and analyze the risk factors. METHODS： A total of 1655 medical staffs were divided into two groups： case group （n = 230） and control group （n = 1425）, according to body check-up reports and liver ultrasonography results. The two groups were then studied for potential risk factors. RESULTS： The overall prevalence of NAFLD reached 13.9%, with 20.7% in male, 10.8% in female. Male staff workers had a higher prevalence of NAFLD than females did （X^2 = 28.70, P 〈 0.001）. Male doctors aged between 50 to 59 had significantly higher prevalence of NAFLD than any other age groups or occupations. The most important unhealthy habits that may lead to fatty liver were decreased exercise, dining out and a lipid-rich diet. CONCLUSION： Metabolic syndrome, obesity,hyperglycemia are highly related to NAFLD. An increase in body mass index （BMI） helps to predict the risk of NAFLD.