急性胰腺炎病因分析

Etiological analysis of acute pancreatitis

目的探讨急性胰腺炎的发病因素,了解其发病特点及发病规律。方法收集我院2004年8月-2009年1月急性胰腺炎患者231例资料,了解其发病因素及各因素的发病率及重症率,以及相关因素,如男女之比、年龄段分布、季节分布等,采用统计学方法进行分析。结果病因中,胆道疾病占43.72%,脂餐或暴食占27.27%,饮酒占16.45%,代谢性疾病占7.36%,其他占5.19%。饮酒者中男女之比为33∶5;胆道疾病中男女之比为47∶54;年龄段分布中以18-44岁年龄段发病率最高,为39.39%;季节分布中各季度例数分别为40,53,70和68,各病因中的重症病例数分别为6,4,6,4,0。结论胆道疾病是本地区急性胰腺炎的首要病因,重视对于胆源性胰腺炎的防治,积极治疗原发病,对于酒精诱发的胰腺为应采取终身禁酒等措施,针对重点人群降低发病率,以提高防治水平。

Objective To conduct etiological study of acute pancreatitis and understand its incidence characteristics and pathogenic law. Methods Data of 231 cases of acute pancreatitis in our hospital from August 2004 to January 2009 were collected. Statistical analysis was carried out in terms of various etiological factors , severe morbidity rate and other correlated factors such as sex ratio, age and season distribution. Results Etiologically, biliary tract disease accounted for 43.72%, fat eating or overeating for 27.27% , alcohol drinking for 16.45% , metabolic diseases for 7.36% and all the other causes for 5. 19%. The ratio between male and female in the alcohol group was 33：5 and in the biliary tract group 47： 54. As for the age distribution, those aged 18 -44 took 39.39%. The number of incidence cases based on season distribution counted 40, 53, 70 and 68 respectively and severe cases in all etiological groups were 6, 4, 6, 4 and 0. Conclusion The leading cause of acute pancreatitis in our region is mainly attributed to the biliary tract diseases. To decrease the incidence rate in the susceptible population, emphasis should be laid upon the early prevention and the exploration of the primary disease. As for alcohol - induced acute pancreatitis, life-long forbidden measures should be enforced.