新疆软紫草水溶性化学成分的研究

Studies on water soluble constituents of Arnebia euchroma(Royle) Johnston

目的:研究新疆软紫草的水溶性化学成分。方法:采用MCL-Gel CHP 20P,Sephadex LH-20和ODS柱色谱技术进行分离纯化,用光谱方法(IR、1H-NMR、13C-NMR、MS)鉴定结构。结果:分离得到3个酚酸类化合物,其结构分别为:化合物Ⅰ[2-(3′-甲氧基-4′-羟基)-苯基-3-羟甲基-6-甲氧基-5-苯并呋喃甲酸]、化合物Ⅱ(咖啡酸四聚体)和化合物Ⅲ(咖啡酸四聚体同分异构体)。结论:化合物Ⅰ为首次从该植物中分离得到。

Objective. To investigate the water soluble constituents of roots from Arnebia euchroma （Royle） Johnston . Methods： Column chromatography（MCL-Gel CHP 20P,Sephadex LH-20 and ODS） were used to isolated and purified the water soluble constituents, and spectroscopic analysis were employed for structure elucidation. Results： Three water soluble constituents were isolated and their structure were elucidated. 2-（3 ＇-trimethoxy-4 -hydroxy）-phenyl-3-hydroxymethyl-6-methoxy-5-benzofuran formic acid（ Ⅰ ） , carfeic acid tetramer（ Ⅱ ） and its isomer（ Ⅲ ）respectively. Conclusion： Compound Ⅰ is found for the first time from this plant.