柔嫩艾美耳球虫秦皇岛和唐山分离株对7种抗球虫药的耐药性

Resistance of Eimeria tenella isolates from Qinhuangdao and Tangshan to seven anticoccidiosis drugs

选择360只14日龄雏鸡,随机分成18组,其中每个分离株均设7个感染用药组,1个感染不用药组,1个不感染不用药组,每组20只,以POAA、RLS、ROP、ACI作为指标。结果显示,除唐山株柔嫩艾美耳球虫仅对氨丙啉和尼卡巴嗪敏感外,秦皇岛株和唐山株对其他药物均产生不同程度的抗药性,其中对球敌均呈现完全抗药性。结果表明,目前在唐山地区可合理地使用氨丙啉和尼卡巴嗪,对其他药物在秦皇岛和唐山两地区须减少或暂停使用。

Three hundred and sixty 14-day-old healthy chickens were selected to study the resistance of Eimeria tenella（E, tenella） isolates（Qinhuangdao and Tangshan isolated） to keqiufen,maduramicin, nicarbazin,amprolium, ruiguanqiu,jinsante and qiudi. The chickens were divided randomly into 18 groups of 20 each,in which of the two both isolates contained 7 medicated groups,one infected and one non-medicated groups, respectively. Based on the percent of optimum anticoccidial activity（ POAA）, reduction of lesion scores（RLS）, relative oocyst production（ROP） and anticoecidial index（ACI）,the results revealed that except E. tenella isolated from Qinhuangdao was sensitive to amprolium and nicarbazin,two E. tenella isolates （Qinhuangdao and Tangshan）were resistant to the seven drugs on different level,both of isolates were complete resistant to qiudi. It is suggested that maduramicin and nicarbazin can be used in Tangshan,the others should not be used at present in Qinhuangdao and Tangshan.