萎缩性阴道炎危险因素

Study on Risk Factors Associated with Atrophic Vaginitis

目的探讨萎缩性阴道炎发病的危险因素。方法应用1∶1配对病例对照研究方法,对52例萎缩性阴道炎患者及52例配对的绝经后妇女进行危险因素调查和统计分析。结果筛选出与萎缩性阴道炎的发生危险因素有绝经年限>10年、高体重指数、清洗外阴方式、反复尿路感染和补充雌激素(P<0.05),进行多因素Logistic回归分析显示入选变量为绝经年限>10年(OR=10.82)、反复尿路感染(OR=3.64)、补充雌激素(OR=0.57)。结论绝经年限长和反复尿路感染是萎缩性阴道炎发生的危险因素,而补充雌激素有保护作用。

Objective To study the risk factors associated with atrophic vaginitis. Method 52 women with atrophic vaginitis and 52 matched menopause control subjects were compared and the results were analyzed using logistic regression analysis. Result The risk factors that were significantly different between the 2 groups were over 10 years after menopause, high body mass index, methods used for genital cleaning, repeated urinary tract infection, and estrogen therapy （P〈0.05）. Logistic regression analysis showed that 10 years after menopause （OR=10.82）, repeated urinary tract infection （0R=3.64） and estrogen therapy （OR=0.57） were significant risk factors. Conclsion Longer years after menopause and repeated urinary tract infection are the risk factors of atrophic vaginitis, but estrogen therapy may have preventive effect for atrophic vaginitis.