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新型低频超声透皮仪设计 被引量:1

Design of New Transdermal Drug Delivery with Low Frequency Ultrasound
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摘要 超声促渗是指运用超声波对人体皮肤产生的空化作用、热效应、声微流作用、辐射压等,促进药物透过皮肤进入软组织的过程。低频超声透皮给药的研究正在成为热点,并开始进入临床,如麻醉给药。为了解决目前超声透皮仪智能化低、安全性差等缺陷设计了一种基于高性能单片机(C8051F340)的智能低频超声经皮给药系统,该系统具有频率、功率和工作方式可调,还有过压和过流保护电路。介绍它的设计原理、硬件结构、软件流程以及具体的实现过程。相关实验取得了很好的效果,表明该系统智能化高,安全性强,实用价值大。 Ultrasound- induced permeability is promoting use of ultrasound on the skin of the air, thermal effects, sound micro - flow, radiation pressure role in promoting access to drugs through the skin and soft tissue process. Application of low- frequency ultrasound - mediated transdermal drug delivery has become a hot research. In order to solve the current transdermal ultrasound instrument of low intelligence,poor security flaws,design a low- frequency ultrasonic transdermal delivery system based on the C8051F340 MCU. The system has a frequency, power adjustable work, over - voltage and over- current protection circuit. The principle of instrument design, the structure of hardware, processes and the specific software implementation process is presented. Practice shows that the system is a highly intelligent, strong safety and has high poractical value of the system and get a good test results.
出处 《现代电子技术》 2009年第16期180-182,共3页 Modern Electronics Technique
关键词 超声发生器 经皮给药 前置放大器 C8051F340 IR2112 ultrasonicator transdermal drug delivery preamplifier C8051F340 IR2112
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  • 1石林,姜藻,吴巍.低频超声治疗肿瘤的机理研究进展[J].实用肿瘤学杂志,2006,20(1):73-75. 被引量:4
  • 2金正均.合并用药中的相加[J].中国药理学报,1980,1:70-73.
  • 3张均田.现代药理实验力方法.北京:北京医科大学中国协和医科大学联合出版社,1998 :927.
  • 4後荣春,周荣华,吕发度,等.SMMC-7721人体肝癌细胞株的述立及其生物学特性的初步观察.第二军医大学学报,1980,(1):5-9.
  • 5王勇,王宗伟,黄兆胜,等.芦荟多糖对肿瘤化疗的增效和减电作用研究.中国新药与临床药理,2002,13(2) :89-9!.
  • 6Nomikou N, Li YS, MoHale A P. I ltrasoun-enhaiicd (Imgdispersion through solid l utmmrs and its possible role inaifiingultrasound-targeted cancer chemotherapy. CiHirer l,Ht, 2010,288( 1 ) :94-98.
  • 7Temizawa M , Kltaia M ,Satslio H ,et al. Irradiation with ultrasound of low output intensity increased chemoKensitivity of subrulaneousslid tumors to an anti-cancer agent. Cancer Lett, 2001 . 173 ( 1 1 ;31-35.
  • 8Mvhr G, Moan J. Synerjjislic' and tumour selective effects offlieiimthrrapv aiu! ultrasound Ireatment. Cancer Iett, 2006, 232(2):206-213.
  • 9Tang H, Faussat AM, Majdak P, et al. Valproic arid inhibitspmlifcmlion andaptosis in acute myeloid leukemia rollsexpressing Pp ainl MKIM . Leukemia ,2004 ,18(7) : 1246-1251.
  • 10Gao ZG, Fain HD, Kapojnul N. Contnilled and targeted tumorchemollierapv by inifellar-encapsnlateland ultrasound. JControl Release,2005 ,102( 1 ) :203-222.

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