N,N'-二-[5-甲氧基-3-溴-2(5H)-4-呋喃酮基]-1,2-乙二胺的合成及其晶体结构(英文)

Synthesis and structure characterization of N,N'-Bis [3-bromo-5-methoxy)-2(5H)-4-furanon-yl]-ethane-1,2-diamine

通过串联迈克尔加成-消除反应合成了N,N'-二-[5-甲氧基-3-溴-2(5H)-4-呋喃酮基]-1,2-乙二胺,利用IR、UV、1HNMR、13C NMR、MS、元素分析和X射线单晶衍射对其进行表征。X射线单晶衍射结果表明:标题化合物包含两个平面的呋喃酮环和两个手性中心,并通过N(1)-H(1A)…O(1)分子间氢键和Br(1)…O(2)近距离作用形成超分子结构。

The 2 （5H）-furanone moieties is prevalent in a variety of natural products and medicinally important compounds, and these compounds have received considerable attention due to their significant biological activities, such as antifungal , antibacterial, and antiinflammatory. Recently, many kinds of 2 （ 5H ） - furanones have emerged as attractive and versatile building blocks in organic synthesis.