联合吸入异丙托溴铵/沙丁胺醇与肝素钠治疗老年AECOPD

Inhaled Compound Ipratropium Bromide Solution and Heparin to treat AECOPD in senile patients

目的评价联合吸入异丙托溴铵/沙丁胺醇针与肝素钠治疗老年患者AECOPD急性加重期疗效。方法将36例AECOPD患者,随机分为雾化联合吸入异丙托溴铵沙丁胺醇针及肝素组(简称联合用药组)与吸入异丙托溴铵沙丁胺醇针组(单用组)。结果36例受试者最终完成试验32例,其中联合用药组16例,单用组16例。治疗前后二组肺功能均有明显改善,联合用药组肺功能改善明显高于单用组,数据具有显著性差异。联合用药组与单用组治疗前后对凝血功能的影响无显著性差异。结论联合吸入异丙托溴铵沙丁胺醇针及肝素有助于缓解慢性阻塞性肺病急性加重,而且对凝血功能影响较小。

Objective To evaluate therapeutic effect of inhaling Compound lpratropium Bromide Solution and Heparin in senile patients with AECOPD. Methods 36 senile patients were randomized into two groups ： inhaling Compound Ipratropium Bromide Solution and Heparin group（ drug combination group） , inhaling Compound lpratrepium Bromide Solution group（ single-drug treatment group）. Results 32 subjects completed treatment in 36 subjects . There were 16 patients separately in both groups. Compare to prior treatment, There were got significant difference in both groups. Drug combination group got greater improvement than Single-drug treatment group in pulmonary function. Conclusion Inhaling Compound Ipratropium Bromide Solution and Heparin rebounds to relieve AECOPD and has little effect to blood clotting funetion.