针刺治疗围绝经期抑郁症的临床研究

A clinical study of the acupuncture treatment in the treatment of perimenopausal depression.

目的观察针刺治疗围绝经期抑郁症的疗效。方法将60例围绝经期抑郁症患者随机分为研究组和对照组各30例。对照组予口服盐酸氟西汀系统治疗。研究组予针刺治疗,每日治疗一次,两周为一疗程,治疗四个疗程,共八周。两组均于治疗前及治疗第2、4、8周末采用汉密尔顿抑郁症状评定量表(HAMD)及副反应量表(TESS)评定临床疗效及不良反应。结果研究组HAMD总分由治疗前(26.84±3.39)分下降至治疗8周后(8.10±5.07)分,对照组由治疗前(25.71±2.56)分下降至8周后(8.52±6.15)分。两组治疗后各周HAMD总分均较治疗前显著减少(P均<0.05)。两组间比较HAMD评分均无显著性差异(P均>0.05)。研究组显效率为66.67%,有效率为96.67%,对照组显效率为73.33%,有效率为93.33%,两组疗效比较差异无显著性(P>0.05)。结论针刺治疗围绝经期抑郁症的疗效较好,无明显不良反应。

Objective To observe clinical therapeutic effects of acupuncture treatment in the treatment of perimenopausal depression. Methods A total 60 patients with perimenopausal depression were randomly divided into control group with fluoxetine and study group with acupuncture for treatment of 8 weeks. HAMD and TESS were used before treatment and at the 2nd,4th and 8th weekend after treatment. Results The scores of HAMD in both groups after treatment were significatly lower than those before treatment, and there were no sigificantly differences between two groups. The total effective rate was 96.67% in study group and 93.33% in control group, no significant difference was found between two groups（P〉 0.05）. Conclusion Acupuncture is effective for perimenopausal depression without severe side effects.