僵人综合征合并多发性骨髓瘤的回顾性分析
摘要
僵人综合征(stiff person syndrome,SPS)是一种罕见的、严重的进行性加重的运动疾病,主要表现为痛性痉挛,对称性的中轴肌强直以及无法控制的肌肉收缩导致的身体畸形。该病与自身免疫有关,其诊断依靠临床表现、肌电图以及高滴度的谷氨酸脱羧酶(GAD)抗体。现将笔者收治的一例僵人综合征合并多发性骨髓瘤(multiple myeloma,MM)报道如下,并结合文献探讨其病因。
出处
《中华急诊医学杂志》
CAS
CSCD
北大核心
2009年第7期765-766,共2页
Chinese Journal of Emergency Medicine
参考文献10
-
1Moersch FP, Woltman HW. Progressive fluctuating muscular rigidity ("stiff-man syndrome") : report of a case and some observations in 13 other cases[J]. Proc Staff Meet Mayo Clin, 1956,31(15):421-427.
-
2Juliana L, Ted MB. Stiffperson syndrome[J]. Pract Neurol,2007,7 (2) : 106-108.
-
3Levy LM, Dalakas MC, Floeter MK. Tile stiff-person syndrome: an autoimmune disorder affccting neurotransmission of gamma-aminobutyric acid[J]. Ann lntem Med, 1999,131(7) : 522-530.
-
4Raju R, Foote J, Banga JP, et al. Analysis of GAD65 autoantibodies in stiff-person syndrome patients [ J ]. J Immunol, 2005, 175 ( 11 ) : 7755- 7762.
-
5Folli F, Solimena M, Cofiell R, et al, Autoantibodies to a 128-kD synaptic protein in three women with the stiff-man syndrome and breast cancer[J]. N Engl J Med, 1993,328(8) :546-551.
-
6Sommer C, Weishaupt A, Brinkhof J, et al. Paraneoplastic stiff-person syndrome:passive transfer to rats by means of lgG antibodies to amphiphysin [J]. Lancet,2005,365(9468) : 1406-1411.
-
7David S, Josep D, Delynne JM. Anti-GAD antibody positive stiff-limb syndrome in multiple myeloma [ J ]. J Neuro-Oncology, 2003, 65 ( 1 ) : 173-175.
-
8Butler MH, Hayashi A, Ohkoshi N, et al. Autoimmunity to gephyrin in Stit/- Man syndrome [ J ]. Neuron, 2000,26 (2) : 307-312.
-
9Howard FM Jr. A new and effective drug in the treatment of stiff-man syndrome:preliminary report[J]. Proc Staff Meet Mayo Clin, 1963, 38 (2) :203-212.
-
10Baker MR, Das M, Isaacs J, et al. Treatment of stiff person syndrome with rituximab [ J ]. J Neurol Neurosurg Psychiatry, 2005,76 (7) : 999- 1001.
-
1马龙.僵人综合征2例误诊分析[J].青海医药杂志,2008,38(6):20-21.
-
2张泽兰,熊先骥.僵人综合征(附2例报告)[J].泸州医学院学报,1991,14(2):134-135. 被引量:1
-
3刘颖,王翠兰,李怡,韩恩吉,李大年.僵肢综合征一例[J].中华神经科杂志,2011,44(9):656-656. 被引量:2
-
4李光勤.药物所致的神经系统运动疾患[J].中国实用内科杂志,1997,17(5):303-304. 被引量:1
-
5李新,王纪佐.帕金森病和运动疾病的研究进展[J].中华神经科杂志,2008,41(10):682-682.
-
6NicholasAFletcher,张菁,李舜伟.其他运动疾病[J].国际内科双语杂志(中英文),2005,5(6):52-55.
-
7张彤.三叉神经痛的病因及病理生理[J].中国麻醉与镇痛,2005,7(1):73-77.
-
8范清秋,封秀琴,赵华.僵人综合征合并多发性骨髓瘤的观察和护理[J].中华护理杂志,2009,44(12):1084-1085. 被引量:2
-
9张生燕,王赞,江新梅.伴发胸腺瘤的僵人综合征1例报告[J].中风与神经疾病杂志,2012,29(6):559-560. 被引量:1
-
10Castelnau P.,Cif L.,Valente E.M.,P. Coubes,袁海峰.苍白球刺激可改善泛酸激酶相关神经变性[J].世界核心医学期刊文摘(神经病学分册),2005,0(9):11-11.