颅内血管外皮细胞瘤的诊断与治疗

Diagnosis and treatment of intracranial hemangiopericytoma

目的加深对颅内血管外皮细胞瘤的诊断、治疗及预后的认识。方法回顾性分析我院自1997年8月至2007年6月收治的经病理证实的11例颅内血管外皮细胞瘸患者的临床资料。结果11例患者中首诊大部分误诊，CT、MR表现类似脑膜瘤，11例患者中8例肿瘤全切除，3例次全切除；术后均行放射治疗，8例随访8个月～5年，复发6例，死亡2例。结论颅内血管外皮细胞瘸是一类血供丰富肿瘤，临床表现类似脑膜瘤，确诊需靠病理和免疫组化；手术切除辅以放疗是其主要治疗手段，但预后不良。

Objective To deepen a further understanding of the diagnosis, treatment and prognosis of intracranial hemangiopericytoma. Methods The clinical data of 11 patients with hemangiopericytoma （ HPC ） from August 1997 to June 2007 proved by operation and pathology were analyzed retrospectively. Results The majority of the eleven patients had been mistakenly diagnosed, and their manifestation on CT or MRI was similar with meningioma, eight patients out of eleven were totally excised of the tumor, and the other three patients were subtotally excised of the tumor; all the patients received radiotherapy after the operation, follow - up was done to eight patients with a period from eight months to five years, and there were six patients recurrance and two patients that have been confirmed to be dead. Conclusions Hemangiopericytoma belongs to a kind of tumor that has abundant blood supply , its clinical manifestation is similar with that of the meningioma, and pathological or immunological chemistry methods should be carried out in order to confirm the diagnosis. The main therapeutic approach is to carry out surgical removal with assisted radiotherapy, but prognosis of intracranial hemangiopericytoma is bad.