夫西地酸乳膏治疗儿童脓疱疮疗效观察

Clinical Observation on Efficacy of 2% Fusidic Acid Cream in the Treatment of Children′s Impetigo

目的观察夫西地酸乳膏治疗儿童脓疱疮的疗效和安全性。方法将2007年6月～2008年6月就诊的100例脓疱疮患儿分为2组,治疗组50例,外搽2%夫西地酸乳膏3次/d,对照组50例,外搽2%莫匹罗星软膏3次/d,疗程均为7天。结果治疗组有效率为94.00%,对照组为92.00%,两组有效率比较,差异无显著性意义(P>0.05),治疗期间均未出现不良反应。结论2%夫西地酸乳膏治疗儿童脓疱疮有效,安全性高。

Objective To evaluate clinical efficacy and safety of 2% Fusidic acid cream in the treatment of children＇s impetigo. Methods 100 patients were enrolled in the test and were divided into 2 groups, 2% Fusidic acid cream was applied topically to the affected areas of the body three times daily for 7days in the treatment group. 2% mupirocin cream was applied topically to the affected areas of the body three times daily for 7days in the control group. Result The effective rate of treatment group was 94%, that for the control was 92%. The difference in clinical efficacy of either group was not statistically significant. There was no any adverse effect observed in the test. Conclusion There is satisfactory clinical efficacy and safety when 2% Fusidic acid cream or 2% mupirocin was treated in children＇s impetigo.