温肾健脾活血利水法治疗慢性肾脏疾病水肿30例

Treatment of Edema in Chronic Kidney Disease with the Chinese Medicine Methods-Warming Yang,Invigorating Spleen,Promoting the Circulation of Blood and Diuresis:30 cases

目的:观察温肾健脾活血利水法治疗慢性肾脏疾病水肿(脾肾阳虚证型)的疗效。方法:将60例慢性肾脏疾病水肿患者(脾肾阳虚证型)分为治疗组和对照组各30例,治疗组给予温肾健脾、活血利水法为主治疗,随症加减。对照组给予百令胶囊。共治疗3周。结果:治疗组痊愈15例,有效12例,无效3例;对照组痊愈7例,有效12例,无效11例。经统计学检验,两组疗效具有显著性差异(P<0.01)。治疗组治疗后心钠素(ANP)水平明显高于治疗前(P<0.01),而对照组治疗前后差异不显著。结论:温肾健脾、活血化瘀、利水消肿三法合用,切中慢性肾脏疾病水肿的主要病机,临床疗效确切,其机制可能与其能提高ANP水平有关。

Objective：To observe the effect of Chinese Medicine on edema in the chronic kidney disease（CKD） treated with warming yang,invigorating spleen, promoting the circulation of blood and diurresis. Methods ：60 patients of CKD with edema were allocated randomly into the treatment group （treated with warming yang, invigorating spleen, promoting the circulation of blood and diuresis） and the control group（ prescription of Bai-ling capsule）. The treatment for tow groups was longed for three weeks. Restdts ：The effect in treatment group （marked effect in 15 cases, effectiveness in 12 cases, failure in 3 cases）was significantly higher than that in the control group （ marked effect in 7 cases, effectiveness in 12 cases, failure in 11 cases） （ P 〈 0. 01 ）. The level of the treatment group in serum had significantly changed after treatment（ P 〈 0.01 ）, as well as no significant difference in the control group. Conclusion：the Chinese Medicine Methods-warming Yang, invigorating spleen, promoting the circulation of blood and diuresis have evident effect on CKD with edema,which mechanism possibly is associated with the increase of the serum level of ANP.