重视胰腺癌的综合治疗

Attach importance to combined therapy for pancreatic cancer

胰腺癌因恶性程度高，病情进展快，预后极差，被称为“癌中之王”。其发病率在全球范围内逐年升高，据美国国立卫生研究院报道，胰腺癌总体1年生存率为8％，5年生存率为3％，中位生存时间仅2～3个月。目前胰腺癌已成为国内外医学界面临的一个重大诊断和治疗难题，任何一种单一的治疗方法均难以取得理想的疗效。国内外多个研究小组正积极开展手术切除联合放、化疗和物理及生物等综合治疗研究，并取得了一定的进展。

Pancreatic cancer is a common malignancy of gastrointestinal system, with features of early metastasis, easy invasion to adjacent tissues and organs and neural metastasis. Therapies include surgery, chemotherapy, radiotherapy, physical and biological therapy and so on. Surgical management, including radical resection and palliative operation, is a major approach. Radiotherapy and chemotherapy could improve the resectional rate and decrease the tumor dissemination. Physical and biological therapies are widely recommended, and there is a rapid progress in zoopery. However, the efficacy of all the therapies is far from satisfactory. Recently, the therapy consisting of surgical resection, radiotherapy, chemotherapy, physical and biological therapy in increasing the long-term survival rate and improving the life quality of patients, along with combined therapy has attracted the attention of surgeons.